Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31014207 | 0.83 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2APKMHTT | |
| SCHEMBL15619063 | 0.82 | ALDH1A1 (0.88) | ALDH1A1MEN1KMT2APKMSMN1; SMN2 | |
| SCHEMBL5563528 | 0.82 | ALDH1A1 (0.86) | ALDH1A1MEN1KMT2APKMSMN1; SMN2 | |
| SCHEMBL12302132 | 0.81 | ALDH1A1 (0.90) | ALDH1A1MEN1KMT2APKMHTT | |
| SCHEMBL18894208 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL31014176 | 0.79 | MEN1 (0.76) | ALDH1A1MEN1KMT2APKMHTT | |
| SCHEMBL8483226 | 0.79 | MEN1 (0.61) | ALDH1A1MEN1KMT2APKMHTT | |
| SCHEMBL19636581 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL29183279 | 0.79 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2APKMHTT | |
| SCHEMBL4503066 | 0.78 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2APKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948780-A | ADMINISTERING A METALLOPROTEINASE INHIBITOR | WARNER-LAMBERT COMPANY (US) | 1999-09-07 | — | — | US | disclosed |