Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | F10 | P00742 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25350384 | 0.83 | ABCB1 (0.63) | KMT2AMAPTSMN1; SMN2MEN1KDM4E | |
| SCHEMBL13561040 | 0.82 | SMN1; SMN2 (0.68) | KMT2AMAPTSMN1; SMN2MEN1KDM4E | |
| SCHEMBL9929102 | 0.79 | HSD17B10 (0.50) | KMT2AMAPTSMN1; SMN2MEN1KDM4E | |
| SCHEMBL17740365 | 0.78 | SMN1; SMN2 (0.70) | KMT2AMAPTSMN1; SMN2MEN1KDM4E | |
| SCHEMBL4129252 | 0.77 | HSD17B10 (0.49) | MAPTKDM4EALDH1A1GAAPOLB | |
| SCHEMBL30810251 | 0.77 | HSD17B10 (0.49) | MAPTKDM4EALDH1A1GAAPOLB | |
| SCHEMBL24118879 | 0.76 | HSPD1 (0.69) | KMT2AMAPTMEN1KDM4EHDAC8 | |
| SCHEMBL6591408 | 0.76 | ALDH1A1 (0.63) | KMT2AMAPTMEN1KDM4EF10 | |
| SCHEMBL24118867 | 0.76 | HSPD1 (0.65) | KMT2AMAPTSMN1; SMN2MEN1KDM4E | |
| SCHEMBL30810187 | 0.76 | HSD17B10 (0.69) | KDM4EALDH1A1HTTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11209328-A | — | — | None | — | — | JP | disclosed |
| JP-H11209328-A | ANILINE DERIVATIVE | YAMANOUCHI PHARMACEUT CO LTD | 1999-08-03 | — | — | JP | disclosed |