Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 10/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11384415 | 0.78 | P2RY1 (0.52) | P2RY1CYP1A2CYP2C19CYP2C9POLB | |
| SCHEMBL1936332 | 0.76 | POLB (0.49) | P2RY1CYP1A2CYP2C19CYP2C9RECQL | |
| SCHEMBL1307522 | 0.74 | P2RY1 (0.54) | P2RY1CYP1A2CYP2C19NPSR1MAPT | |
| SCHEMBL6560226 | 0.74 | P2RY1 (0.57) | P2RY1CYP1A2CYP2C19NPSR1KMT2A | |
| SCHEMBL22719499 | 0.74 | P2RY1 (0.57) | P2RY1CYP1A2CYP2C19NPSR1KMT2A | |
| SCHEMBL921315 | 0.73 | POLB (0.51) | P2RY1CYP1A2CYP2C19CYP2C9RECQL | |
| SCHEMBL15170108 | 0.73 | MAPT (0.48) | P2RY1CYP1A2CYP2C19CYP2C9NPSR1 | |
| SCHEMBL8720576 | 0.73 | MAPT (0.48) | P2RY1CYP1A2CYP2C19CYP2C9RECQL | |
| SCHEMBL8724391 | 0.73 | CTSS (0.49) | P2RY1CYP1A2CYP2C19CYP2C9RECQL | |
| SCHEMBL9798371 | 0.73 | LTA4H (0.54) | CYP1A2CYP2C19CYP2C9POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939359-A | Herbicidal pyrazine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-17 | — | — | US | disclosed |
| EP-0773934-A1 | HERBICIDAL PYRAZINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996003391-A1 | HERBICIDAL PYRAZINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-08 | — | — | WO | disclosed |