Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 5/20 | 0.42 |
| ▸ | JAK2 | O60674 | 5/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | RGS12 | O14924 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30590084 | 0.82 | ALDH1A1 (0.38) | JAK1JAK2ADORA3ADORA2BPNP | |
| SCHEMBL14743922 | 0.77 | ADORA3 (0.48) | JAK1JAK2ADORA3ADORA2BJAK3 | |
| SCHEMBL30618111 | 0.76 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8671444 | 0.66 | ADORA3 (0.48) | JAK1JAK2ADORA3ADORA2BCDK2 | |
| SCHEMBL6435319 | 0.64 | NR1I2 (0.39) | PNP | |
| SCHEMBL17186330 | 0.64 | PIK3C2A (0.34) | PNPCDK2CDK9 | |
| SCHEMBL4560684 | 0.64 | ADORA3 (0.35) | JAK1JAK2ADORA3ADORA2BRGS12 | |
| SCHEMBL4658220 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL17186495 | 0.63 | PIK3C2A (0.34) | PNPCDK2CDK9 | |
| SCHEMBL3237727 | 0.63 | PNP (0.30) | PNPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874578-A | Process for preparing guanine-containing antiviral agents and purinyl salts useful in such process | BRISTOL-MYERS SQUIBB (US) | 1999-02-23 | — | — | US | disclosed |