Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 10/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2525378 | 0.78 | BIRC5 (0.30) | — | |
| SCHEMBL14976487 | 0.78 | MAP4K4 (0.31) | MAP4K4 | |
| SCHEMBL1643517 | 0.76 | MAP4K4 (0.46) | MAP4K4PLGF12F11KLKB1 | |
| SCHEMBL1476448 | 0.76 | NFE2L2 (0.33) | MAP4K4 | |
| SCHEMBL1644263 | 0.76 | MAP4K4 (0.37) | MAP4K4PLGF12F11KLKB1 | |
| SCHEMBL1477713 | 0.74 | RORB (0.37) | MEN1 | |
| SCHEMBL1477143 | 0.74 | SCN9A (0.39) | — | |
| Bicarbonate SCHEMBL14829490 | 0.73 | NAPRT (0.37) | — | |
| SCHEMBL1477483 | 0.73 | CYP2A6 (0.40) | MAP4K4NOS3NOS1NOS2 | |
| SCHEMBL1476408 | 0.73 | MEN1 (0.35) | MAP4K4MEN1PSIP1AXLMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11209379-A | — | — | None | — | — | JP | disclosed |
| JP-H11209379-A | SUPEROXIDE DETECTION REAGENT | ATOO KK | 1999-08-03 | — | — | JP | disclosed |