SCHEMBL8340925

SCHEMBL8340925

CCc1cc(Br)ccc1S(=O)(=O)Nc1ccc(C(F)(F)F)c(O[C@@H]2CCN(C)C2)c1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 18/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8339797 0.89 UTS2R (0.71) UTS2R
SCHEMBL8339810 0.85 UTS2R (0.70) UTS2R
SCHEMBL6820879 0.85 UTS2R (0.70) UTS2R
SCHEMBL8342760 0.84 UTS2R (0.67) UTS2R
SCHEMBL8342929 0.83 UTS2R (0.73) UTS2R
SCHEMBL8342516 0.83 UTS2R (0.68) UTS2R
SCHEMBL5835165 0.82 UTS2R (1.00) UTS2R
SCHEMBL5835254 0.82 UTS2R (0.74) UTS2R
SCHEMBL5835169 0.82 UTS2R (1.00) UTS2R
SCHEMBL5835257 0.82 UTS2R (0.74) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043366-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed