SCHEMBL83411

SCHEMBL83411

O=c1[nH]c2ccccc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 1/20 0.59
ALDH1A1 P00352 4/20 0.56
KDM4E B2RXH2 3/20 0.56
HPGD P15428 2/20 0.56
CYP3A4 P08684 1/20 0.56
ALOX15 P16050 1/20 0.56
PSMB8 P28062 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
PDE3B Q13370 3/20 0.50
PDE3A Q14432 3/20 0.50
PGR P06401 2/20 0.49
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
GRIN1 Q05586 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44
GRIN2C Q14957 1/20 0.44
GRIN3A Q8TCU5 1/20 0.44
TNKS O95271 1/20 0.43
TNKS2 Q9H2K2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29667911 1.00 CMA1 (0.59) CMA1ALDH1A1KDM4EHPGDCYP3A4
SCHEMBL4622486 0.98 CMA1 (0.57) CMA1ALDH1A1KDM4EHPGDCYP3A4
Hydrochloric Acid SCHEMBL27353717 0.98 CMA1 (0.57) CMA1ALDH1A1KDM4EHPGDCYP3A4
Hydrochloric Acid SCHEMBL4566776 0.98 CMA1 (0.57) CMA1ALDH1A1KDM4EHPGDCYP3A4
Bromide SCHEMBL9589695 0.98 CMA1 (0.57) CMA1ALDH1A1KDM4EHPGDCYP3A4
Bicarbonate SCHEMBL6185434 0.92 CMA1 (0.52) CMA1ALDH1A1KDM4EHPGDCYP3A4
SCHEMBL6424321 0.88 CMA1 (0.53) CMA1ALDH1A1KDM4EHPGDCYP3A4
SCHEMBL11571393 0.82 LMNA (0.48) CMA1ALDH1A1KDM4EHPGDCYP3A4
SCHEMBL7096191 0.81 CMA1 (0.42) CMA1ALDH1A1KDM4EHPGDCYP3A4
Phthalazinone SCHEMBL26920198 0.76 ALDH1A1 (0.64) CMA1ALDH1A1KDM4EHPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3398 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4611899-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Petra Pharma Corporation (US) 2025-09-10 EP claimed
EP-4562018-A1 COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE Biogen MA Inc. (US) 2025-06-04 EP claimed
CN-119948036-A Compounds for the treatment of huntington's disease 渤健马萨诸塞州股份有限公司 2025-05-06 CN claimed
US-20250137160-A1 ANODIZED ENCLOSURE WITH FINGERPRINT RESISTANT SEALING TECHNOLOGY APPLE INC. 2025-05-01 US claimed
CN-119907204-A Anodized shell with fingerprint resistant sealing technique 苹果公司 2025-04-29 CN claimed
WO-2025072485-A1 INKJET PRINTING PROCESSES FOR TEMPORARY TATTOOS Prism Inks, Inc. (US) 2025-04-03 WO claimed
US-20250108658-A1 INKJET PRINTING PROCESSES FOR TEMPORARY TATTOOS Prism Inks, Inc. (US) 2025-04-03 US claimed
EP-4514784-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Petra Pharma Corporation (US) 2025-03-05 EP claimed
CN-119301106-A Allosteric benzopyrone inhibitors of phosphoinositide 3-kinase (PI 3K) for the treatment of disease 佩特拉制药公司 2025-01-10 CN claimed
CN-119274851-A Composite conductive material and preparation method and application thereof 深圳圣安技术有限公司 2025-01-07 CN claimed
US-4328235-A SUPPRESSION OF PAIN BOEHRINGER INGELHEIM GMBH (DE) 1982-05-04 US claimed
US-4323677-A LEGUME PLANT GROWTH REGULATOR MONSANTO COMPANY (US) 1982-04-06 US claimed
EP-0040398-A2 Process for preparing 3-substituted 2(3H)-benzothiazolones or 2(3H)-naphthothiazolones HOECHST AKTIENGESELLSCHAFT (DE) 1981-11-25 EP claimed
EP-0039818-A1 Substituted 2-(3H)-benzothiazolones, processes for their preparation, their utilization in the preparation of medicines and medicines containing them Dr. Karl Thomae GmbH (DE) 1981-11-18 EP claimed
EP-0039440-A1 Medicines containing substituted benzothiazol-2-(3H)-ones Dr. Karl Thomae GmbH (DE) 1981-11-11 EP claimed
US-4283508-A Fragrant prevulcanization inhibitors MONSANTO COMPANY (US) 1981-08-11 US claimed
EP-0022213-A1 Medicaments containing benzothiazole-2(3H)-one derivatives Dr. Karl Thomae GmbH (DE) 1981-01-14 EP claimed
EP-0001503-B1 ANTITHROMBOTIC COMPOSITIONS CONTAINING BENZISOTHIAZOLONES BEECHAM GROUP PLC (GB) 1981-01-07 EP claimed
EP-0003075-A1 N-Amides of 2-benzothiazolinone and their use as plant growth regulants MONSANTO COMPANY (US) 1979-07-25 EP claimed
US-3994733-A CYANINE DYES, A BENZOTHIAZOLE, OR BENZOTHIAZOLONE, OR NAPHTHOTHIAZOLE, OR NAPHTHOTHIAZOLONE, OR A QUINOLONE FUJI PHOTO FILM CO., LTD. (JA) 1976-11-30 US claimed