Known targets — ChEMBL curated mechanism
ACHESCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconic Acid SCHEMBL27654138 | 1.00 | LMNA (0.74) | LMNAPDE4AUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL27730141 | 0.98 | LMNA (0.71) | LMNAPDE4AUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL28154944 | 0.96 | LMNA (0.74) | LMNAPDE4AUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL27896954 | 0.96 | LMNA (0.74) | LMNAPDE4AUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL303216 | 0.94 | LMNA (0.77) | LMNAPDE4AUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL2266761 | 0.94 | LMNA (0.77) | LMNAPDE4AUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL5861529 | 0.94 | LMNA (0.77) | LMNAPDE4AUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL21835970 | 0.94 | LMNA (0.77) | LMNAPDE4AUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL22653997 | 0.92 | LMNA (0.74) | LMNAPDE4AUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL22653996 | 0.92 | LMNA (0.74) | LMNAPDE4AUSP2SLCO1B1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015023-A2 | RECOVERY PROCESS | KIWI CO-OPERATIVE DAIRIES LIMITED (NZ) | 1999-04-01 | — | — | WO | disclosed |