Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.38 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.38 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968318 | 0.84 | TAAR1 (0.52) | PTPN1CA2ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6964713 | 0.81 | GLA (0.45) | CA2ALDH1A1THRBPPARGKDM4E | |
| SCHEMBL8340297 | 0.80 | PTPN1 (0.48) | PTPN1CA2ALDH1A1PPARGNPSR1 | |
| SCHEMBL6960171 | 0.78 | GLA (0.44) | CA2ALDH1A1THRBPPARGKDM4E | |
| SCHEMBL8337064 | 0.78 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2THRBGAALYPLA1 | |
| SCHEMBL6583573 | 0.78 | PPARG (0.54) | CA2ALDH1A1SMN1; SMN2THRBGAA | |
| SCHEMBL6971454 | 0.77 | GLA (0.43) | CA2ALDH1A1THRBPPARGKDM4E | |
| SCHEMBL8182679 | 0.76 | PTPN1 (0.79) | PTPN1CA2ALDH1A1PPARGKDM4E | |
| SCHEMBL6583581 | 0.76 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2THRBGAAPPARG | |
| SCHEMBL8340601 | 0.74 | PTPN1 (0.47) | PTPN1CA2HTTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965589-A | AN ACTIVE MATERIAL HAVING HYPOGLYCEMIC ACTIVITY AND BLOOD LIPID LOWERING ACTIVITY, FOR USE AS AN ANTIDIABETIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-12 | — | — | US | disclosed |