Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | LYPLA1 | O75608 | 2/20 | 0.40 |
| ▸ | LYPLA2 | O95372 | 2/20 | 0.40 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583021 | 0.83 | PPARG (0.51) | PPARGGAATSHRLMNAMAPK1 | |
| SCHEMBL7160661 | 0.81 | GLA (0.45) | PPARGSMN1; SMN2MAPK1MAPT | |
| SCHEMBL8896521 | 0.80 | TUBB4A (0.51) | PPARGLYPLA1LYPLA2ABHD16AGAA | |
| SCHEMBL6584822 | 0.80 | PPARG (0.49) | PPARGGAATSHRLMNAMAPK1 | |
| SCHEMBL6052119 | 0.79 | PPARG (0.59) | PPARGSMN1; SMN2TSHRLMNAMAPK1 | |
| SCHEMBL6587646 | 0.79 | PPARG (0.59) | PPARGSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6583749 | 0.79 | PPARG (0.47) | PPARGTSHRTP53ALDH1A1CA2 | |
| SCHEMBL8794891 | 0.78 | GLA (0.44) | PPARGSMN1; SMN2MAPK1MAPT | |
| SCHEMBL6583581 | 0.78 | SMN1; SMN2 (0.42) | PPARGLYPLA1LYPLA2ABHD16ASMN1; SMN2 | |
| SCHEMBL8341871 | 0.78 | PTPN1 (0.53) | PPARGLYPLA1LYPLA2ABHD16ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |