Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.36 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.36 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.36 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15302656 | 0.83 | CYP2D6 (0.39) | CYP2D6MAPK1CYP2C19LMNACYP1A2 | |
| SCHEMBL15302915 | 0.74 | KIF11 (0.43) | CYP2D6MAPK1KMT2AALDH1A1TSHR | |
| SCHEMBL15302642 | 0.73 | RIPK1 (0.40) | CYP2D6MAPK1CYP2C19CYP1A2KDM4E | |
| SCHEMBL11723481 | 0.72 | SCN5A (0.43) | HTTALDH1A1GAA | |
| SCHEMBL15302653 | 0.72 | SCN5A (0.43) | HTTALDH1A1GAA | |
| SCHEMBL11755112 | 0.72 | SCN5A (0.43) | HTTALDH1A1GAA | |
| SCHEMBL15302254 | 0.72 | SCN5A (0.43) | HTTALDH1A1GAA | |
| SCHEMBL27615947 | 0.70 | MAPT (0.47) | CYP2D6MAPK1CYP2C19LMNACYP1A2 | |
| SCHEMBL7787243 | 0.70 | ESR2 (0.42) | CYP2D6MAPK1CYP2C19LMNACYP1A2 | |
| SCHEMBL1078987 | 0.68 | PTPN1 (0.36) | CYP2D6MAPK1CYP2C19KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999005986-A1 | IMPROVED DENTAL FLOSS | WHITEHILL ORAL TECHNOLOGIES, INC. (US) | 1999-02-11 | — | — | WO | disclosed |