Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | FURIN | P09958 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861293 | 0.85 | FURIN (0.46) | HTTL3MBTL1TDP1SMN1; SMN2FURIN | |
| SCHEMBL29808710 | 0.85 | TDP1 (0.44) | TDP1SMN1; SMN2FURINLMNAALDH1A1 | |
| SCHEMBL5104173 | 0.85 | TDP1 (0.44) | TDP1SMN1; SMN2FURINLMNAALDH1A1 | |
| SCHEMBL8143862 | 0.84 | FURIN (0.41) | TDP1SMN1; SMN2FURINALDH1A1MEN1 | |
| SCHEMBL4551023 | 0.84 | HTT (0.47) | HTTL3MBTL1TDP1SMN1; SMN2SOS1 | |
| SCHEMBL62179 | 0.84 | AKR1C3 (0.46) | HTTTDP1SMN1; SMN2POLBFURIN | |
| SCHEMBL7133728 | 0.84 | CYP3A4 (0.44) | TDP1SMN1; SMN2FURINLMNAALDH1A1 | |
| SCHEMBL17576543 | 0.79 | FURIN (0.37) | TDP1SMN1; SMN2FURINALDH1A1PGR | |
| SCHEMBL7136291 | 0.79 | FURIN (0.53) | TDP1SMN1; SMN2FURINLMNAALDH1A1 | |
| SCHEMBL17577475 | 0.78 | MAPK1 (0.42) | HTTTDP1SMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001951-A | Aromatic polycarbodiimide and film thereof | NITTO DENKO CORPORATION (JP) | 1999-12-14 | — | — | US | disclosed |
| EP-0915109-A1 | Aromatic polycarbodiimide and film thereof | NITTO DENKO CORPORATION (JP) | 1999-05-12 | — | — | EP | disclosed |