SCHEMBL7136291

SCHEMBL7136291

O=C=Nc1ccc(Oc2cccc(Oc3ccc(N=C=O)cc3)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FURIN P09958 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.48
ALDH1A1 P00352 2/20 0.48
MEN1 O00255 1/20 0.48
MITF O75030 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
GFER P55789 1/20 0.48
KMT2A Q03164 1/20 0.48
NLRP1 Q9C000 1/20 0.48
NOD2 Q9HC29 1/20 0.48
CYP3A4 P08684 2/20 0.44
TSHR P16473 1/20 0.44
TRPA1 O75762 1/20 0.43
F2 P00734 1/20 0.42
F10 P00742 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
MAPK1 P28482 1/20 0.41
TNKS O95271 1/20 0.40
PARP15 Q460N3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1861293 0.93 FURIN (0.46) FURINSMN1; SMN2ALDH1A1MEN1MITF
SCHEMBL242048 0.88 LTA4H (0.50) CYP3A4TSHRPARP10
SCHEMBL26555121 0.88 MAOB (0.58) FURINSMN1; SMN2ALDH1A1MEN1MITF
SCHEMBL50333 0.88 CYP3A4 (0.54) FURINALDH1A1MEN1MAPTKMT2A
SCHEMBL4544188 0.88 CYP3A4 (0.54) FURINALDH1A1MEN1MAPTKMT2A
SCHEMBL4551613 0.88 CYP3A4 (0.54) FURINALDH1A1MEN1MAPTKMT2A
SCHEMBL7133728 0.86 CYP3A4 (0.44) FURINSMN1; SMN2ALDH1A1MEN1MITF
SCHEMBL10609821 0.84 LTA4H (0.46) FURINALDH1A1MAPT
SCHEMBL29808710 0.84 TDP1 (0.44) FURINSMN1; SMN2ALDH1A1MEN1MITF
SCHEMBL5104173 0.84 TDP1 (0.44) FURINSMN1; SMN2ALDH1A1MEN1MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9188660-A None JP disclosed
EP-0792897-B1 Aromatic polycarbodiimide and films thereof NITTO DENKO CORP (JP) 2003-08-13 EP disclosed
EP-1281727-A1 SOLUBLE POLYIMIDE AND COMPOSITION COMPRISING THE SAME, BONDING SHEET, ADHESIVE LAMINATED FILM FOR COVERING ACCELERATOR BEAM TUBE, AND ADHESIVE LAMINATED FILM FOR COVERING CONDUCTOR WIRE FOR ACCELERATOR QUENCH HEATER Kaneka Corporation (JP) 2003-02-05 EP disclosed
US-6313258-B1 Aromatic polycarbodiimide and films thereof NITTO DENKO CORPORATION (JP) 2001-11-06 US disclosed
EP-0792897-A1 Aromatic polycarbodiimide and films thereof NITTO DENKO CORPORATION (JP) 1997-09-03 EP disclosed
JP-H09188660-A AROMATIC DIISOCYANATE NITTO DENKO CORP 1997-07-22 JP disclosed
US-4059580-A Sulphonated polybenz-1,3-oxazin-2,4-diones BAYER AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed