Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 3/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342145 | 1.00 | DAGLB (0.49) | DAGLBPREPACE2FKBP1ATMEM97 | |
| SCHEMBL3119462 | 1.00 | DAGLB (0.49) | DAGLBPREPACE2FKBP1ATMEM97 | |
| SCHEMBL3130196 | 0.98 | PREP (0.50) | DAGLBPREPACE2NPSR1TSHR | |
| SCHEMBL1873488 | 0.89 | PREP (0.52) | DAGLBPREPACE2NPSR1TSHR | |
| SCHEMBL7939228 | 0.89 | PREP (0.52) | DAGLBPREPACE2NPSR1TSHR | |
| SCHEMBL6597133 | 0.89 | PREP (0.52) | DAGLBPREPACE2NPSR1TSHR | |
| SCHEMBL3354292 | 0.86 | PREP (0.54) | PREPACE2FKBP1ATMEM97SIGMAR1 | |
| SCHEMBL14646665 | 0.84 | TMEM97 (0.56) | PREPACE2FKBP1ATMEM97SIGMAR1 | |
| SCHEMBL19621551 | 0.84 | TMEM97 (0.56) | PREPACE2FKBP1ATMEM97SIGMAR1 | |
| SCHEMBL1873676 | 0.83 | PREP (0.53) | PREPACE2NPSR1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5917034-A | Antithrombotic n-amidinopiperidine and benzamidine derivatives | PFIZER INC. (US) | 1999-06-29 | — | — | US | disclosed |