Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.79 |
| ▸ | HRH2 | P25021 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | ATP4A | P20648 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | ATP4B | P51164 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342390 | 1.00 | ACHE (0.79) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| SCHEMBL10426600 | 0.90 | ACHE (0.78) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| Bromide SCHEMBL8943997 | 0.89 | ACHE (0.76) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| Iodide SCHEMBL8743624 | 0.89 | ACHE (0.76) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| Hydrochloric Acid SCHEMBL8743619 | 0.89 | ACHE (0.76) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| Nizatidine SCHEMBL770 | 0.89 | ACHE (1.00) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| Nizatidine SCHEMBL13575816 | 0.89 | ACHE (1.00) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| Nizatidine SCHEMBL9241933 | 0.89 | ACHE (1.00) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| Nizatidine SCHEMBL769 | 0.89 | ACHE (1.00) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| Nizatidine SCHEMBL28102651 | 0.88 | ACHE (0.94) | ACHEHRH2MEN1SLC22A1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981757-A | Nizatidine preparation | TORCAN CHEMICAL LTD. (CA) | 1999-11-09 | — | — | US | claimed |
| US-5541335-A | Process for preparing nizatidine | TORCAN CHEMICAL LTD. (CA) | 1996-07-30 | — | — | US | claimed |
| US-5981757-A | Nizatidine preparation | TORCAN CHEMICAL LTD. (CA) | 1999-11-09 | — | — | US | disclosed |
| US-5981757-A | Nizatidine preparation | TORCAN CHEMICAL LTD. (CA) | 1999-11-09 | — | — | US | disclosed |
| EP-0641763-B1 | NOVEL QUATERNARY AMMONIUM SALTS AND USE THEREOF AS MEDICINE | ZERIA PHARM CO LTD (JP) | 1997-01-08 | — | — | EP | disclosed |
| US-5574054-A | GASTROINTESTINAL DISORDERS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |
| US-5541335-A | Process for preparing nizatidine | TORCAN CHEMICAL LTD. (CA) | 1996-07-30 | — | — | US | disclosed |
| EP-0641763-A1 | NOVEL QUATERNARY AMMONIUM SALTS AND USE THEREOF AS MEDICINE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |