Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346864 | 0.86 | KMT2A (0.57) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL8345591 | 0.83 | HTT (0.59) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL8343426 | 0.78 | FGFR1 (0.56) | RAB9ASMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL8346644 | 0.75 | FGFR1 (0.60) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL8346599 | 0.73 | FGFR1 (0.60) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL8347592 | 0.73 | CYP19A1 (0.51) | KMT2AALDH1A1HTT | |
| SCHEMBL8346813 | 0.73 | FGFR1 (0.47) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL3496264 | 0.73 | HTT (0.72) | RAB9ASMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL8343829 | 0.72 | AR (0.52) | RAB9ASMN1; SMN2MAPTCYP1A2CYP2C9 | |
| SCHEMBL366895 | 0.71 | HTT (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958950-A | CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1999-09-28 | — | — | US | claimed |
| US-5958950-A | CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1999-09-28 | — | — | US | disclosed |