SCHEMBL6407

SCHEMBL6407

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nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.67
LMNA P02545 2/20 0.61
L3MBTL1 Q9Y468 1/20 0.52
TDP1 Q9NUW8 1/20 0.50
USP2 O75604 1/20 0.50
SLCO1B1 Q9Y6L6 1/20 0.50
KDM4E B2RXH2 2/20 0.38
OR51E2 Q9H255 1/20 0.35
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8343201 1.00 PDE4A (0.67) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL28350552 1.00 PDE4A (0.67) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL29356160 1.00 PDE4A (0.67) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL17144675 1.00 PDE4A (0.67) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL10338405 0.98 PDE4A (0.64) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL15121486 0.98 PDE4A (0.64) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL15121487 0.98 PDE4A (0.64) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL5077868 0.98 PDE4A (0.64) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL725570 0.98 PDE4A (0.64) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL20591201 0.98 PDE4A (0.64) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 674 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118055752-A Personal cleansing compositions containing organic acids having pKa greater than 2.7 宝洁公司 2024-05-17 CN claimed
CN-111801088-B Personal care compositions and uses 宝洁公司 2024-03-08 CN claimed
EP-4291155-A1 MULTI-PHASE SHAMPOO COMPOSITION WITH AN AESTHETIC DESIGN The Procter & Gamble Company (US) 2023-12-20 EP claimed
CN-117083049-A Multiphase shampoo compositions with aesthetic design 宝洁公司 2023-11-17 CN claimed
CN-112469387-B Personal cleansing compositions, methods and uses 宝洁公司 2023-07-14 CN claimed
US-11684558-B2 Personal care composition preservatives level optimization THE PROCTER & GAMBLE COMPANY (US) 2023-06-27 US claimed
CN-111278511-B Compact shampoo compositions 宝洁公司 2023-06-02 CN claimed
WO-2023070501-A1 PERSONAL CLEANSING COMPOSITION WITH AN ORGANIC ACID HAVING A PKA GREATER THAN 2.7 THE PROCTER & GAMBLE COMPANY (US) 2023-05-04 WO claimed
US-20230135226-A1 PERSONAL CLEANSING COMPOSITION WITH AN ORGANIC ACID HAVING A PKA GREATER THAN 2.7 THE PROCTER & GAMBLE COMPANY 2023-05-04 US claimed
US-11633340-B2 2023-04-25 US claimed
CN-101687338-A Preservative compositions for wood and like materials GENICS INC 2010-03-31 CN claimed
EP-2117789-A1 PRESERVATIVE COMPOSITIONS FOR WOOD AND LIKE MATERIALS Genics, Inc. (CA) 2009-11-18 EP claimed
WO-2008086604-A1 PRESERVATIVE COMPOSITIONS FOR WOOD AND LIKE MATERIALS GENICS, INC. (CA) 2008-07-24 WO claimed
US-6712995-B2 MIXTURE OF ALKANOLAMINE, SURFACTANTS IN AQUEOUS SOLUTION SIKA SCHWEIZ AG (CH) 2004-03-30 US claimed
EP-0957071-B1 A method for rehabilitative and/or protective corrosion-inhibition of reinforcing steel embedded in a hardened concrete structure by means of surface-applied corrosion-inhibiting compositions SIKA SCHWEIZ AG (CH) 2004-03-24 EP claimed
US-20030034479-A1 Method for rehabilitative and/or protective corrosion-inhibition of reinforcing steel embedded in a hardened concrete structure by means of surface-applied corrosion-inhibiting compositions SIKA SCHWEIZ AG (CH) 2003-02-20 US claimed
US-6402990-B1 AMINO- AND/OR HYDROXYALKYLAMINO COMPOUND(S), WHICH ARE PARTIALLY OR COMPLETELY NEUTRALIZED WITH ONE OR MORE INORGANIC ACID(S) AND/OR AROMATIC CARBOXYLIC ACID(S); SURFACTANTS; ORGANOSILICONES AS WATER REPELLENT SIKA AG, VORM, KASPAR WINKLER & CO. (CH) 2002-06-11 US claimed
US-20020066889-A1 METHOD FOR REHABILITATIVE AND/OR PROTECTIVE CORROSION-INHIBITION OF REINFORCING STEEL EMBEDDED IN A HARDENED STRUCTURE BY MEANS OF SURFACE-APPLIED CORROSION-INHIBITING COMPOSITIONS SIKA AG VORM, KASPAR WINKLER & CO. (CH) 2002-06-06 US claimed
EP-0957071-A1 A method for rehabilitative and/or protective corrosion-inhibition of reinforcing steel embedded in a hardened concrete structure by means of surface-applied corrosion-inhibiting compositions Sika AG, vorm. Kaspar Winkler & Co. (CH) 1999-11-17 EP claimed
EP-0538193-B1 Condensed cycloaliphatir-amidino-hydrazon salts as S-adenosylmethionin decarboxylase inhibitors CIBA GEIGY AG (CH) 1996-12-04 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11684558-B2 Personal care composition preservatives level optimization CUTA, SMURF1, POLR1C PDE4A 2407/4885LMNA 783/4885L3MBTL1 3751/4885
US-11633340-B2 SMURF1, SUCLG1, S100P PDE4A 3483/4885LMNA 2102/4885L3MBTL1 3773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.