Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 8/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | LDHB | P07195 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607582 | 0.92 | LDHA (0.42) | LDHAHTTKDM4ETDP1MEN1 | |
| SCHEMBL6603142 | 0.85 | LDHA (0.41) | LDHAHTTKDM4ETDP1MEN1 | |
| SCHEMBL6607008 | 0.75 | LDHA (0.54) | LDHALDHB | |
| SCHEMBL7451110 | 0.74 | LDHA (0.41) | LDHALDHBLMNA | |
| SCHEMBL6606214 | 0.74 | LDHA (0.43) | LDHAHTTMEN1KMT2AMAPT | |
| SCHEMBL6604999 | 0.73 | LDHA (0.42) | LDHATDP1LDHB | |
| SCHEMBL6606818 | 0.72 | LDHA (0.43) | LDHAKDM4ETDP1MEN1KMT2A | |
| SCHEMBL6603774 | 0.72 | LDHA (0.48) | LDHAKMT2ALDHB | |
| SCHEMBL6607615 | 0.72 | LDHA (0.44) | LDHALDHB | |
| SCHEMBL6608000 | 0.71 | LDHA (0.53) | LDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936128-A | BENZENETHIOL COMPOUNDS AS INTERMEDIATES; BACTERICIDES, VIRICIDES; HIV | WARNER-LAMBERT COMPANY (US) | 1999-08-10 | — | — | US | disclosed |