Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 2/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.50 |
| ▸ | ITGAL | P20701 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 8/20 | 0.47 |
| ▸ | MMP9 | P14780 | 8/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346758 | 0.91 | TACR1 (0.51) | MMP2MMP9GHSR | |
| SCHEMBL8346990 | 0.90 | TACR1 (0.53) | KMT2AMEN1 | |
| SCHEMBL8345542 | 0.89 | TACR1 (0.55) | — | |
| SCHEMBL8343109 | 0.89 | TACR1 (0.55) | — | |
| SCHEMBL8345475 | 0.89 | TACR1 (0.42) | ITGB2ICAM1ITGALMMP2MMP9 | |
| SCHEMBL8346929 | 0.85 | TACR1 (0.56) | GHSR | |
| SCHEMBL8349377 | 0.85 | TACR1 (0.48) | MMP9GHSR | |
| SCHEMBL7399209 | 0.84 | GHSR (0.47) | MMP2MMP9ACEGHSR | |
| SCHEMBL8345132 | 0.83 | TACR1 (0.53) | MMP9GHSR | |
| SCHEMBL8344898 | 0.82 | TACR1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869489-A | TREATMENT OF INFLAMMATORY DISEASES, MIGRAINES AND ASTHMA | MERCK & CO., INC. (US) | 1999-02-09 | — | — | US | disclosed |