Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.53 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.53 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.53 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.53 |
| ▸ | STIM2 | Q9P246 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345184 | 0.89 | TRPC1 (0.67) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL8344850 | 0.88 | ALDH1A1 (0.75) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL6313469 | 0.86 | MAPT (0.63) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL8341452 | 0.85 | HTT (0.56) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL6052641 | 0.85 | ALDH1A1 (0.60) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL3323394 | 0.84 | ALDH1A1 (0.58) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL15167569 | 0.84 | ALDH1A1 (0.61) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL5680826 | 0.83 | ALDH1A1 (0.60) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL8339357 | 0.83 | ALDH1A1 (0.60) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL1065124 | 0.82 | ALDH1A1 (0.75) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014181287-A1 | HETEROCYCLYL COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2014-11-13 | — | — | WO | disclosed |
| US-5888941-A | Carbozamides with antifungal activity | J. URIACH & CIA. S.A. (ES) | 1999-03-30 | — | — | US | disclosed |
| EP-0783502-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-07-16 | — | — | EP | disclosed |
| WO-1997005131-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |