Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12892124 | 0.87 | HPGDS (0.43) | ACKR3CAPN1STSKMT2AKDM4E | |
| SCHEMBL8343817 | 0.83 | KDM2B (0.51) | ACKR3CAPN1STSKMT2AKDM4E | |
| SCHEMBL2906679 | 0.78 | KDM4E (0.50) | KMT2AKDM4EPKMHPGDSCHRNB2 | |
| SCHEMBL2901762 | 0.78 | KDM4E (0.46) | ACKR3KMT2AKDM4EPKMHPGDS | |
| SCHEMBL2901764 | 0.78 | KDM4E (0.46) | ACKR3KMT2AKDM4EPKMHPGDS | |
| SCHEMBL2902476 | 0.78 | KDM4E (0.46) | ACKR3KMT2AKDM4EPKMHPGDS | |
| SCHEMBL12892122 | 0.76 | ITGB3 (0.45) | KDM4EPKMHPGDSGPR119HTT | |
| SCHEMBL2905053 | 0.76 | KDM4E (0.48) | KMT2AKDM4EPKMHPGDSCHRNB2 | |
| SCHEMBL2905047 | 0.76 | KDM4E (0.48) | KMT2AKDM4EPKMHPGDSCHRNB2 | |
| SCHEMBL2905050 | 0.76 | KDM4E (0.48) | KMT2AKDM4EPKMHPGDSCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020435-A1 | PIPERIDINYL COMPOUNDS THAT SELECTIVELY BIND INTEGRINS | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-03-11 | — | — | WO | disclosed |