Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102641 | 0.83 | ATM (0.52) | HSD17B10SMN1; SMN2ALDH1A1CA1CA2 | |
| SCHEMBL125621 | 0.81 | PBRM1 (0.87) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL29363032 | 0.81 | PBRM1 (0.87) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL5091376 | 0.81 | PBRM1 (0.65) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL9282073 | 0.81 | PBRM1 (0.87) | PBRM1F2PLGPRSS1PRSS2 | |
| 3-Aminobenzoic Acid SCHEMBL27648 | 0.79 | PBRM1 (0.69) | PBRM1F2PLGPRSS1PRSS2 | |
| 3-Aminobenzamide SCHEMBL16070 | 0.79 | PBRM1 (0.63) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL9101086 | 0.79 | PBRM1 (0.83) | PBRM1F2PLGPRSS1PRSS2 | |
| 3-Aminobenzoic Acid SCHEMBL8003706 | 0.79 | PBRM1 (0.69) | PBRM1F2PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8643223 | 0.79 | PBRM1 (0.83) | PBRM1F2PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109971210-B | Phenolic azo type reactive dye and preparation method thereof | 南京林业大学 | 2021-04-20 | — | — | CN | disclosed |
| CN-109971209-B | Amino naphthol sulfonic acid azo type reactive dye and preparation method thereof | 南京林业大学 | 2020-12-04 | — | — | CN | disclosed |
| CN-109971210-A | A kind of phenols azo reactive dye and preparation method thereof | 南京林业大学 | 2019-07-05 | — | — | CN | disclosed |
| EP-2308854-A1 | 2,3,6-trisubstituted-4-pyrimidone derivatives | Sanofi-Aventis (FR) | 2011-04-13 | — | — | EP | disclosed |
| WO-2004085408-A1 | 2, 3, 6-TRISUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2004-10-07 | — | — | WO | disclosed |