SCHEMBL102641

SCHEMBL102641

O=C(F)c1cccc(C(=O)F)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CES2 O00748 3/20 0.48
CES1 P23141 2/20 0.48
PARP1 P09874 2/20 0.44
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
GAA P10253 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA6 P23280 1/20 0.42
CA9 Q16790 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
RAB9A P51151 1/20 0.42
HDAC6 Q9UBN7 2/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC8 Q9BY41 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22832275 0.92 ATM (0.65) ATMTDP1L3MBTL1CES2CES1
SCHEMBL2981120 0.90 CA12 (0.58) ATMTDP1L3MBTL1KMT2AMEN1
SCHEMBL21332072 0.87 KMO (0.56) CES2CES1GAAHDAC8
SCHEMBL28151817 0.85 CA12 (0.64) PARP1KMT2AMEN1GAAHSD17B10
SCHEMBL10703733 0.85 CES2 (0.71) L3MBTL1CES2CES1PARP1KMT2A
SCHEMBL10833546 0.83 PARP1 (0.63) L3MBTL1PARP1KMT2AMEN1GAA
SCHEMBL8344640 0.83 PBRM1 (0.61) TDP1PARP1HSD17B10CA12CA1
SCHEMBL27634276 0.83 TP53BP1 (0.45) ATMTDP1L3MBTL1CES2CES1
SCHEMBL6821235 0.83 CES2 (0.40) ATMTDP1L3MBTL1CES2CES1
SCHEMBL27647771 0.81 KMO (0.67) ATMTDP1L3MBTL1GAAHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120005190-A Polyamide-imide resin, polyamide-imide resin film, and process for producing the same 中化学科学技术研究有限公司 2025-05-16 CN claimed
CN-118359507-A Stable isotope labeled m-phenylenediamine15N2Is synthesized by the method of (2) 上海化工研究院有限公司 2024-07-19 CN claimed
CN-111836849-B Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2023-04-07 CN claimed
EP-3762447-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2021-01-13 EP claimed
CN-111836849-A Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2020-10-27 CN claimed
WO-2019170529-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2019-09-12 WO claimed
CN-120005191-A Polyamide-imide resin and process for producing polyamide-imide resin film 中化学科学技术研究有限公司 2025-05-16 CN disclosed
CN-120005190-A Polyamide-imide resin, polyamide-imide resin film, and process for producing the same 中化学科学技术研究有限公司 2025-05-16 CN disclosed
CN-118359507-A Stable isotope labeled m-phenylenediamine15N2Is synthesized by the method of (2) 上海化工研究院有限公司 2024-07-19 CN disclosed
CN-111836849-B Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2023-04-07 CN disclosed
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP disclosed
EP-3762447-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2021-01-13 EP disclosed
CN-111836849-A Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2020-10-27 CN disclosed
EP-0372656-B1 Polymers comprising spirolactam units SHELL INT RESEARCH (NL) 1995-06-07 EP disclosed
US-4992526-A Preparation of polyarylate polymers of hydroxyaryl-substituted 1,6-diaza [4.] spirodilactams SHELL OIL COMPANY (US) 1991-02-12 US disclosed
US-4977235-A From aromatic dicarboxylic acids and hydroxyaryl-substituted 1,6-diaza(4.4)spirodilactams; molding materials; high glass transition temperatures SHELL OIL COMPANY (US) 1990-12-11 US disclosed
US-4968768-A Polyestercarbonate polymer containing spirodi lactam moiety SHELL OIL COMPANY (US) 1990-11-06 US disclosed
EP-0372656-A2 Polymers comprising spirolactam units SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-06-13 EP disclosed
US-4910285-A Polyarylate polymers SHELL OIL COMPANY (US) 1990-03-20 US disclosed
US-4555370-A CYANTATION OF ACYL. FLUORIDE BAYER AKTIENGESELLSCHAFT (DE) 1985-11-26 US disclosed