Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14016355 | 0.86 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAKDM4ECYP2C19MAPT | |
| SCHEMBL2706623 | 0.86 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAKDM4ECYP2C19MAPT | |
| SCHEMBL9754962 | 0.73 | MAPT (0.36) | LMNACYP2C9KDM4ECYP2C19MAPT | |
| SCHEMBL8540868 | 0.73 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL4859696 | 0.72 | KDM4E (0.39) | SMN1; SMN2LMNAKDM4ECYP2C19MAPT | |
| SCHEMBL2691041 | 0.72 | — | — | |
| SCHEMBL11837084 | 0.71 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL38953 | 0.71 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAKDM4ECYP2C19 | |
| SCHEMBL19261516 | 0.69 | KDM4E (0.39) | LMNAKDM4ECYP2C19MAPT | |
| Water SCHEMBL7733637 | 0.69 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAKDM4ECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379494-B1 | FUSED BICYCLIC OR TRICYCLIC AMINO ACIDS | WARNER LAMBERT CO (US) | 2010-03-10 | — | — | EP | disclosed |
| WO-2004016260-A1 | THERAPEUTIC USE OF FUSED BICYCLIC OR TRICYCLIC AMINO ACIDS | PFIZER LIMITED (GB) | 2004-02-26 | — | — | WO | disclosed |