Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706623 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2 | |
| SCHEMBL14016355 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2 | |
| SCHEMBL8344752 | 0.73 | SMN1; SMN2 (0.35) | SMN1; SMN2 | |
| SCHEMBL25179633 | 0.71 | — | — | |
| SCHEMBL2691041 | 0.65 | — | — | |
| SCHEMBL4859696 | 0.65 | KDM4E (0.39) | SMN1; SMN2 | |
| SCHEMBL21570661 | 0.65 | — | — | |
| SCHEMBL11837084 | 0.65 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL616425 | 0.65 | TP53 (0.32) | SMN1; SMN2 | |
| SCHEMBL38953 | 0.65 | SMN1; SMN2 (0.56) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882044-A1 | 1,4-DIHYDROPYRIDINE COMPOUNDS AS BRADYKININ ANTAGONISTS | PFIZER INC. (US) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997030048-A1 | 1,4-DIHYDROPYRIDINE COMPOUNDS AS BRADYKININ ANTAGONISTS | PFIZER PHARMACEUTICALS INC. (JP) | 1997-08-21 | — | — | WO | disclosed |