Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.54 |
| ▸ | REN | P00797 | 4/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PEPD | P12955 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.54 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3919811 | 0.90 | ACE (0.68) | ACERENPTGS1LMNAHSD17B10 | |
| SCHEMBL11331490 | 0.90 | ACE (0.68) | ACERENPTGS1LMNAHSD17B10 | |
| SCHEMBL11563443 | 0.90 | ACE (0.68) | ACERENPTGS1LMNAHSD17B10 | |
| SCHEMBL9052964 | 0.90 | ACE (0.68) | ACERENPTGS1LMNAHSD17B10 | |
| Acetic Acid SCHEMBL11338123 | 0.86 | ACE (0.67) | ACERENPTGS1LMNAHSD17B10 | |
| Acetic Acid SCHEMBL11324915 | 0.86 | ACE (0.67) | ACERENPTGS1LMNAHSD17B10 | |
| SCHEMBL30248996 | 0.85 | ACE (0.61) | ACERENPTGS1LMNAHSD17B10 | |
| SCHEMBL17352471 | 0.79 | OPRM1 (0.39) | ACERENPTGS1LMNAHSD17B10 | |
| SCHEMBL7377082 | 0.79 | ACE (0.82) | ACERENPTGS1LMNAHSD17B10 | |
| SCHEMBL29615405 | 0.79 | ACE (0.61) | ACERENPTGS1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5986074-A | CHELATE COMPOUNDS AS IMAGING AGENTS AND KITS | EMORY UNIVERSITY (US) | 1999-11-16 | — | — | US | claimed |
| US-5955053-A | TECHNETIUM OR RHENIUM CHELATES WITH LIGANDS SUCH AS DITHIOUREA, CYSTEINYLETHYLENE OR THIOACETAMIDETHIOUREA FOR IMAGES | EMORY UNIVERSITY (US) | 1999-09-21 | — | — | US | claimed |
| US-5986074-A | CHELATE COMPOUNDS AS IMAGING AGENTS AND KITS | EMORY UNIVERSITY (US) | 1999-11-16 | — | — | US | disclosed |
| US-5955053-A | TECHNETIUM OR RHENIUM CHELATES WITH LIGANDS SUCH AS DITHIOUREA, CYSTEINYLETHYLENE OR THIOACETAMIDETHIOUREA FOR IMAGES | EMORY UNIVERSITY (US) | 1999-09-21 | — | — | US | disclosed |