Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 2/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342792 | 0.87 | HDAC1 (0.48) | HDAC1HDAC2KLK7KLK5FOLH1 | |
| Hydrochloric Acid SCHEMBL8349173 | 0.85 | CALCRL (0.44) | HDAC1HDAC2MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL7764108 | 0.85 | CALCRL (0.44) | HDAC1HDAC2MMP2MMP9 | |
| SCHEMBL8344872 | 0.81 | FOLH1 (0.48) | KLK7KLK5FOLH1CPB1CPB2 | |
| SCHEMBL8348620 | 0.78 | KLK7 (0.51) | KLK7KLK5FOLH1CPB1CPB2 | |
| SCHEMBL7761836 | 0.78 | ANPEP (0.60) | HDAC1HDAC2FOLH1 | |
| SCHEMBL8345432 | 0.77 | HDAC1 (0.51) | HDAC1HDAC2FOLH1SIRT5PTGER4 | |
| Hydrochloric Acid SCHEMBL7759030 | 0.77 | ANPEP (0.59) | HDAC1HDAC2FOLH1 | |
| SCHEMBL22804062 | 0.71 | FOLH1 (0.63) | FOLH1CPB1CPB2MMP2MMP9 | |
| SCHEMBL11064441 | 0.71 | CAPN1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883121-A | INHIBITING ACTIVITY AGAINST CATHEPSIN, AND IS USEFUL FOR PREVENTION AND TREATMENT OF OSTEOPATHY SUCH AS OSTEOPOROSIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |