Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7761841 | 0.84 | F2 (0.45) | MMP9CA1CA2CPB2 | |
| SCHEMBL8344933 | 0.81 | HDAC1 (0.51) | FOLH1MMP2MMP9KLK7KLK5 | |
| SCHEMBL8345432 | 0.78 | HDAC1 (0.51) | FOLH1PTGER4 | |
| SCHEMBL17397643 | 0.78 | MAPT (0.62) | FOLH1KLK7KLK5MAPT | |
| SCHEMBL8349145 | 0.77 | HDAC1 (0.49) | FOLH1PTGER4 | |
| SCHEMBL7203421 | 0.75 | CTSL (0.50) | MMP9PTGER4 | |
| SCHEMBL8205976 | 0.75 | CTSL (0.50) | MMP9PTGER4 | |
| SCHEMBL7764101 | 0.75 | DPP8 (0.62) | FOLH1MMP2MMP9 | |
| SCHEMBL16762202 | 0.75 | FOLH1 (0.52) | FOLH1MMP2MMP9CA1CA2 | |
| Hydrochloric Acid SCHEMBL7762718 | 0.74 | DPP8 (0.61) | FOLH1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883121-A | INHIBITING ACTIVITY AGAINST CATHEPSIN, AND IS USEFUL FOR PREVENTION AND TREATMENT OF OSTEOPATHY SUCH AS OSTEOPOROSIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |