Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.69 |
| ▸ | RAB9A | P51151 | 12/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.69 |
| ▸ | PKM | P14618 | 4/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.69 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | MMP2 | P08253 | 1/20 | 0.67 |
| ▸ | MMP9 | P14780 | 1/20 | 0.67 |
| ▸ | MMP8 | P22894 | 1/20 | 0.67 |
| ▸ | MMP13 | P45452 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.55 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11314470 | 0.91 | NPC1 (0.66) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3337159 | 0.88 | MMP2 (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL18890639 | 0.88 | MMP2 (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL19626159 | 0.86 | NPC1 (0.69) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL25138044 | 0.85 | NPC1 (0.68) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL17821446 | 0.84 | MMP2 (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL17821350 | 0.84 | MMP2 (0.55) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL172216 | 0.83 | NPC1 (1.00) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30634854 | 0.83 | NPC1 (1.00) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30561047 | 0.83 | NPC1 (1.00) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045279-B1 | AMINE OXIDE COMPOUNDS, PROCESSES FOR THEIR MANUFACTURE AND THEIR USE AS OPTICAL BRIGHTENERS | CIBA-GEIGY AG (CH) | 1988-06-01 | — | — | EP | claimed |
| EP-0006271-B2 | WASHING AND SOFTENING COMPOSITIONS CONTAINING NONIONIC BRIGHTENER | THE PROCTER & GAMBLE COMPANY (US) | 1986-01-22 | — | — | EP | claimed |
| EP-0029003-B1 | SALTS OF CATIONIC BRIGHTENERS, THEIR PREPARATION AND THEIR USE ON ORGANIC MATERIALS AS WELL AS THEIR CONCENTRATED AQUEOUS SOLUTIONS | CIBA-GEIGY AG (CH) | 1984-12-05 | — | — | EP | claimed |
| EP-0006271-B1 | WASHING AND SOFTENING COMPOSITIONS CONTAINING NONIONIC BRIGHTENER | THE PROCTER & GAMBLE COMPANY (US) | 1982-03-31 | — | — | EP | claimed |
| EP-0045279-A1 | Amine oxide compounds, processes for their manufacture and their use as optical brighteners | CIBA-GEIGY AG (CH) | 1982-02-03 | — | — | EP | claimed |
| EP-0029003-A2 | Salts of cationic brighteners, their preparation and their use on organic materials as well as their concentrated aqueous solutions | CIBA-GEIGY AG (CH) | 1981-05-20 | — | — | EP | claimed |
| EP-0006271-A1 | Washing and softening compositions containing nonionic brightener | THE PROCTER & GAMBLE COMPANY (US) | 1980-01-09 | — | — | EP | claimed |
| CN-117820341-A | Preparation method of bio-based fluorescent whitening agent | 中科国生(杭州)科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | GILEAD SCIENCES, INC. | 2008-03-27 | — | — | US | disclosed |
| US-20070249840-A1 | Process for the preparation of bis-benzazolyl compounds | ELIU VICTOR P | 2007-10-25 | — | — | US | disclosed |
| US-20070249840-A1 | Process for the preparation of bis-benzazolyl compounds | ELIU VICTOR P | 2007-10-25 | — | — | US | disclosed |
| WO-1999015608-A1 | SOFTENING COMPOSITIONS CONTAINING OPTICAL BRIGHTENERS | 3V SIGMA S.P.A. (IT) | 1999-04-01 | — | — | WO | disclosed |
| EP-0045279-B1 | AMINE OXIDE COMPOUNDS, PROCESSES FOR THEIR MANUFACTURE AND THEIR USE AS OPTICAL BRIGHTENERS | CIBA-GEIGY AG (CH) | 1988-06-01 | — | — | EP | disclosed |
| US-4433975-A | HETEROCYCLIC QUATERNARY AMMONIUM PHOSPHATES | CIBA-GEIGY CORPORATION (US) | 1984-02-28 | — | — | US | disclosed |
| US-4432886-A | 2-FURANYLBENZIMIDAZOLE, OR 2-AZOLYLBENZIMIDAZOLE, OR 2-STILBENYLBENZIMIDAZOLE, OR 2,5-(BENZIMIDAZOLYL)FURAN PHOSPHATES | CIBA-GEIGY CORPORATION (US) | 1984-02-21 | — | — | US | disclosed |
| US-4384121-A | WATER SOLUBLE | CIBA-GEIGY CORPORATION (US) | 1983-05-17 | — | — | US | disclosed |
| EP-0006271-B1 | WASHING AND SOFTENING COMPOSITIONS CONTAINING NONIONIC BRIGHTENER | THE PROCTER & GAMBLE COMPANY (US) | 1982-03-31 | — | — | EP | disclosed |
| EP-0045279-A1 | Amine oxide compounds, processes for their manufacture and their use as optical brighteners | CIBA-GEIGY AG (CH) | 1982-02-03 | — | — | EP | disclosed |
| EP-0029003-A2 | Salts of cationic brighteners, their preparation and their use on organic materials as well as their concentrated aqueous solutions | CIBA-GEIGY AG (CH) | 1981-05-20 | — | — | EP | disclosed |
| EP-0006271-A1 | Washing and softening compositions containing nonionic brightener | THE PROCTER & GAMBLE COMPANY (US) | 1980-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | TYMP, PNP, PIKFYVE | NPC1 1365/4885RAB9A 2959/4885ALDH1A1 2788/4885 |
| US-20070249840-A1 | Process for the preparation of bis-benzazolyl compounds | HBZ, H1-3, HBS1L | NPC1 3829/4885RAB9A 2925/4885ALDH1A1 2585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.