Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345010 | 0.73 | ALDH1A1 (0.35) | ALDH1A1GAAMAPTHPGDBRD4 | |
| SCHEMBL8343212 | 0.71 | CCR1 (0.32) | BRD4 | |
| SCHEMBL30625233 | 0.69 | — | — | |
| SCHEMBL26602715 | 0.69 | — | — | |
| SCHEMBL12382830 | 0.67 | AAK1 (0.39) | AAK1HPGDGABRA1GABRG2GABRB3 | |
| SCHEMBL20780218 | 0.66 | — | — | |
| SCHEMBL30625223 | 0.66 | KDM4E (0.33) | ALDH1A1GAAHPGDGABRA1GABRG2 | |
| SCHEMBL26602768 | 0.66 | KDM4E (0.33) | ALDH1A1GAAHPGDGABRA1GABRG2 | |
| SCHEMBL30625252 | 0.65 | — | — | |
| SCHEMBL30625103 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014384-A2 | CYCLIC COMPOUNDS CONTAINING ZINC BINDING GROUPS AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |