Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341421 | 0.92 | GPR17 (0.74) | GPR17ALOX15KDM4EMEN1ALDH1A1 | |
| SCHEMBL9341007 | 0.92 | GPR17 (0.74) | GPR17ALOX15KDM4EMEN1ALDH1A1 | |
| SCHEMBL9397608 | 0.90 | GPR17 (0.61) | GPR17ALOX15KDM4EMEN1ALDH1A1 | |
| SCHEMBL9397604 | 0.90 | GPR17 (0.61) | GPR17ALOX15KDM4EMEN1ALDH1A1 | |
| SCHEMBL9395874 | 0.88 | GPR17 (0.56) | GPR17ALOX15KDM4EMEN1ALDH1A1 | |
| SCHEMBL8344673 | 0.88 | GPR17 (0.58) | GPR17ALOX15KDM4EMEN1ALDH1A1 | |
| SCHEMBL8486573 | 0.86 | GPR17 (0.51) | GPR17ALOX15KDM4EMEN1ALDH1A1 | |
| SCHEMBL8344945 | 0.85 | GPR17 (0.84) | GPR17ALOX15KDM4EMEN1ALDH1A1 | |
| SCHEMBL8344952 | 0.84 | KDM4E (0.83) | GPR17ALOX15KDM4EMEN1ALDH1A1 | |
| SCHEMBL9397491 | 0.83 | GPR17 (0.56) | GPR17ALOX15KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919811-A | NEURODEGENERATIVE DISORDERS | GLAXO WELLCOME S.P.A. (IT) | 1999-07-06 | — | — | US | disclosed |