Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8347016 | 0.83 | HSP90B1 (0.33) | HSP90B1HSP90AA1HSP90AB1TRAP1 | |
| SCHEMBL6165069 | 0.82 | RECQL (0.30) | — | |
| SCHEMBL6968462 | 0.81 | — | — | |
| SCHEMBL6966628 | 0.81 | DRD2 (0.34) | DRD2HTR2AHTR7HTR6HSP90B1 | |
| SCHEMBL6159218 | 0.81 | — | — | |
| SCHEMBL6973184 | 0.80 | DRD2 (0.32) | DRD2HTR2AHTR7HTR6 | |
| SCHEMBL6163272 | 0.80 | HSP90B1 (0.33) | DRD2HTR2AHTR7HTR6HSP90B1 | |
| SCHEMBL6966324 | 0.79 | — | — | |
| SCHEMBL6963215 | 0.78 | HSP90B1 (0.32) | DRD2HTR2AHTR7HTR6HSP90B1 | |
| SCHEMBL6162374 | 0.78 | HSP90B1 (0.32) | DRD2HTR2AHTR7HTR6HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |