Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11782006 | 0.85 | PTGER1 (0.46) | HCAR2ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27905848 | 0.84 | PTGDR2 (0.47) | HCAR2PTGDR2ABL1NPC1RAB9A | |
| SCHEMBL28849093 | 0.84 | HCAR2 (0.42) | HCAR2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL29846096 | 0.82 | HCAR2 (0.48) | HCAR2NR4A2 | |
| SCHEMBL28854654 | 0.82 | HCAR2 (0.48) | HCAR2NR4A2 | |
| SCHEMBL29631019 | 0.76 | NPC1 (0.45) | HCAR2ABL1NPC1RAB9AMEN1 | |
| SCHEMBL20894099 | 0.76 | NPC1 (0.45) | HCAR2ABL1NPC1RAB9AMEN1 | |
| SCHEMBL16703334 | 0.76 | PTPN11 (0.59) | HCAR2NPC1RAB9ASMN1; SMN2DAO | |
| SCHEMBL9642872 | 0.74 | HCAR2 (0.52) | HCAR2DAOHDAC6KDM4EALDH1A1 | |
| SCHEMBL14109159 | 0.74 | GPR52 (0.50) | ABL1HDAC6NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888941-A | Carbozamides with antifungal activity | J. URIACH & CIA. S.A. (ES) | 1999-03-30 | — | — | US | disclosed |