Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | MITF | O75030 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 4/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11474550 | 1.00 | KDM4E (0.66) | KDM4EMEN1MITFALDH1A1MAPT | |
| SCHEMBL11475306 | 0.91 | KDM4E (0.62) | KDM4EMEN1MITFALDH1A1MAPT | |
| SCHEMBL11475309 | 0.91 | KDM4E (0.62) | KDM4EMEN1MITFALDH1A1MAPT | |
| SCHEMBL28869394 | 0.85 | MAOB (0.63) | KDM4EMEN1MITFALDH1A1MAPT | |
| SCHEMBL8562396 | 0.82 | CA12 (0.63) | KDM4EMEN1MITFALDH1A1MAPT | |
| SCHEMBL8562393 | 0.82 | CA12 (0.63) | KDM4EMEN1MITFALDH1A1MAPT | |
| SCHEMBL22579360 | 0.82 | MAOB (0.59) | KDM4EMEN1MITFALDH1A1MAPT | |
| SCHEMBL3680910 | 0.81 | TTR (0.49) | KDM4EMEN1MITFALDH1A1MAPT | |
| SCHEMBL10845152 | 0.80 | TBXAS1 (0.69) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL10845148 | 0.80 | TBXAS1 (0.69) | MEN1KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014381-A2 | MATRIX METALLOPROTEINASE INHIBITORS AND METHODS FOR IDENTIFICATION OF LEAD COMPOUNDS | WARNER-LAMBERT COMPANY LLC. (US) | 2004-02-19 | — | — | WO | disclosed |
| US-4226878-A | ANTIINFLAMMATORY, HYPOTENSIVES, ANTIHISTAMINES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1980-10-07 | — | — | US | disclosed |