Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.57 |
| ▸ | ITGAV | P06756 | 3/20 | 0.57 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | C3AR1 | Q16581 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905452 | 0.94 | ITGB3 (0.60) | ITGB3ITGA2BITGAVITGB1ITGB6 | |
| SCHEMBL3688040 | 0.88 | ITGB3 (0.72) | ITGB3ITGA2BITGAVITGB1ITGB6 | |
| SCHEMBL13074861 | 0.87 | ITGB3 (0.58) | ITGB3ITGA2BITGAVITGB1ITGB6 | |
| SCHEMBL8347405 | 0.86 | ITGB3 (0.49) | ITGB3ITGA2BITGAVNAMPTC3AR1 | |
| SCHEMBL2900012 | 0.83 | ITGB3 (0.61) | ITGB3ITGA2BITGAVITGB1ITGB6 | |
| SCHEMBL2902210 | 0.82 | ITGB3 (0.59) | ITGB3ITGA2BITGAVBCHEACHE | |
| SCHEMBL2899066 | 0.80 | ITGB3 (0.69) | ITGB3ITGA2BITGAVITGB1ITGB6 | |
| SCHEMBL10154221 | 0.79 | ITGB3 (0.53) | ITGB3ITGA2BITGAVNAMPTC3AR1 | |
| SCHEMBL2905930 | 0.78 | ITGB3 (0.85) | ITGB3ITGA2BITGAVBCHEACHE | |
| SCHEMBL2905958 | 0.76 | ITGB3 (0.56) | ITGB3ITGA2BITGAVITGB1ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020435-A1 | PIPERIDINYL COMPOUNDS THAT SELECTIVELY BIND INTEGRINS | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-03-11 | — | — | WO | disclosed |