Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | C3AR1 | Q16581 | 3/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154221 | 0.93 | ITGB3 (0.53) | ITGB3ITGA2BALDH1A1C3AR1ITGAV | |
| SCHEMBL8345381 | 0.86 | ITGB3 (0.57) | ITGB3ITGA2BC3AR1ITGAVNAMPT | |
| SCHEMBL2905452 | 0.79 | ITGB3 (0.60) | ITGB3ITGA2BC3AR1ITGAVNAMPT | |
| SCHEMBL10189890 | 0.79 | ITGAV (0.70) | ITGB3ITGA2BITGAV | |
| SCHEMBL12892147 | 0.76 | GPR119 (0.51) | ITGB3ITGA2BALDH1A1NAMPT | |
| SCHEMBL16299411 | 0.76 | ITGB3 (0.49) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8343883 | 0.74 | ITGB3 (0.45) | ITGB3ITGA2BALDH1A1ITGAVNAMPT | |
| SCHEMBL10154215 | 0.73 | ITGB3 (0.50) | ITGB3ITGA2BALDH1A1ITGAV | |
| SCHEMBL8346693 | 0.73 | ITGB3 (0.37) | ITGB3ITGA2BALDH1A1ITGAVNAMPT | |
| SCHEMBL2899739 | 0.72 | ITGB3 (0.72) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539739-B1 | PIPERIDINYL COMPOUNDS THAT SELECTIVELY BIND INTEGRINS | JANSSEN PHARMACEUTICA NV (BE) | 2010-11-24 | — | — | EP | disclosed |
| WO-2004020435-A1 | PIPERIDINYL COMPOUNDS THAT SELECTIVELY BIND INTEGRINS | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-03-11 | — | — | WO | disclosed |