Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TRPC1 | P48995 | 2/20 | 0.55 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.55 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.55 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.55 |
| ▸ | STIM2 | Q9P246 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2325526 | 0.89 | MAPT (0.76) | MAPTALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL6405411 | 0.84 | ALDH1A1 (0.60) | MAPTALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL5680826 | 0.84 | ALDH1A1 (0.60) | MAPTALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL6407442 | 0.84 | ALDH1A1 (0.56) | MAPTALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL1402909 | 0.83 | HTT (0.52) | MAPTALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL1402681 | 0.82 | TRPC1 (0.53) | MAPTALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL6403552 | 0.82 | ALDH1A1 (0.57) | MAPTALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL6527991 | 0.82 | ALDH1A1 (0.81) | MAPTALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL31636462 | 0.82 | ALDH1A1 (0.57) | MAPTALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL8341374 | 0.81 | MAPT (0.55) | MAPTSMN1; SMN2KMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888941-A | Carbozamides with antifungal activity | J. URIACH & CIA. S.A. (ES) | 1999-03-30 | — | — | US | disclosed |
| WO-1997005131-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |