SCHEMBL8345558

SCHEMBL8345558

C=CCCSSSSSCCC=C

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TRPA1 O75762 2/20 0.38
CYP3A4 P08684 2/20 0.38
HPGD P15428 2/20 0.38
ALOX15 P16050 1/20 0.35
TSHR P16473 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8352486 0.97 ALDH1A1 (0.40) ALDH1A1TRPA1CYP3A4HPGDALOX15
SCHEMBL29904771 0.90 ALDH1A1 (0.47) ALDH1A1TRPA1CYP3A4HPGDALOX15
SCHEMBL7591242 0.83 ALDH1A1 (0.41) ALDH1A1TRPA1CYP3A4HPGDALOX15
SCHEMBL29904772 0.73 TRPA1 (0.43) ALDH1A1TRPA1CYP3A4HPGDALOX15
SCHEMBL6282537 0.73
SCHEMBL18196053 0.73
SCHEMBL544944 0.69
SCHEMBL392677 0.67 TRPA1 (0.80) ALDH1A1TRPA1CYP3A4HPGDALOX15
SCHEMBL389755 0.67 TRPA1 (0.80) ALDH1A1TRPA1CYP3A4HPGDALOX15
SCHEMBL2987869 0.67 TRPA1 (0.80) ALDH1A1TRPA1CYP3A4HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999021008-A1 PHARMACEUTICAL GRADE GARLIC PHARMAPRINT, INC. (US) 1999-04-29 WO disclosed