Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 3/20 | 0.32 |
| ▸ | DHFR | P00374 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961234 | 0.80 | TYMS (0.34) | ALOX12LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8345126 | 0.77 | MEN1 (0.33) | ALOX12LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7085415 | 0.67 | TP53 (0.39) | ALOX12LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7086123 | 0.66 | TYMS (0.37) | LMNACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8346906 | 0.65 | MEN1 (0.38) | — | |
| SCHEMBL6965870 | 0.65 | ALDH1A1 (0.33) | ALOX12LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6972756 | 0.64 | TYMS (0.41) | LMNACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7079911 | 0.63 | SLC2A1 (0.34) | TP53RXFP1TYMSDHFRKDM4E | |
| SCHEMBL6972910 | 0.63 | ALDH1A1 (0.35) | LMNACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7078935 | 0.62 | SLC6A9 (0.34) | ALOX12LMNACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |