Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343488 | 0.87 | GPR35 (0.39) | GPR35ALDH1A1HTTNPC1MAPK1 | |
| SCHEMBL11241133 | 0.86 | MAPT (0.47) | GPR35ALDH1A1HTTNPC1MAPK1 | |
| SCHEMBL1935934 | 0.82 | ALDH1A1 (0.44) | GPR35ALDH1A1HTTNPC1MAPK1 | |
| SCHEMBL4237765 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HTTNPC1MAPK1RAB9A | |
| SCHEMBL28473346 | 0.80 | ALDH1A1 (0.46) | GPR35ALDH1A1HTTMAPK1TDP1 | |
| SCHEMBL8347607 | 0.80 | CD69 (0.43) | GPR35ALDH1A1HTTNPC1MAPK1 | |
| SCHEMBL15851025 | 0.79 | GPR35 (0.41) | GPR35ALDH1A1HTTNPC1MAPK1 | |
| SCHEMBL8350127 | 0.79 | GPR35 (0.41) | GPR35ALDH1A1HTTNPC1MAPK1 | |
| SCHEMBL11927735 | 0.77 | CA12 (0.46) | ALDH1A1HTTNPC1MAPK1RAB9A | |
| SCHEMBL689862 | 0.76 | ALDH1A1 (0.54) | GPR35ALDH1A1HTTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981800-A | Preparation process for 4-substituted dinitroanilines | CFPI AGRO (FR) | 1999-11-09 | — | — | US | disclosed |