Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4836281 | 0.92 | DRD3 (0.43) | LMNADRD3DRD2HRH3MEN1 | |
| SCHEMBL4838546 | 0.82 | LMNA (0.42) | LMNADRD3DRD2HRH3MEN1 | |
| SCHEMBL18119910 | 0.80 | SIRT6 (0.45) | LMNAMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL2297329 | 0.80 | SIRT6 (0.45) | LMNAMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL2292301 | 0.80 | SIRT6 (0.45) | LMNAMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL15109816 | 0.76 | USP30 (0.43) | LMNADRD3DRD2MEN1KMT2A | |
| SCHEMBL972020 | 0.74 | DRD3 (0.47) | DRD3 | |
| SCHEMBL10747371 | 0.73 | PDE10A (0.46) | DRD3DRD2 | |
| SCHEMBL24394471 | 0.71 | PDE10A (0.47) | DRD3MEN1KMT2A | |
| SCHEMBL2293905 | 0.71 | PDE10A (0.47) | DRD3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999023197-A1 | PROCESSES OF SOAKING FABRICS WITH A LIQUID AQUEOUS PERSULFATE SALT-CONTAINING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-14 | — | — | WO | claimed |
| WO-1999023196-A1 | LIQUID AQUEOUS BLEACHING COMPOSITIONS PACKAGED IN A UV RESISTANT CONTAINER | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-14 | — | — | WO | claimed |
| WO-1999023195-A1 | MULTI-PURPOSE LIQUID AQUEOUS BLEACHING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-14 | — | — | WO | claimed |
| EP-0915150-A1 | Processes of soaking fabrics with a liquid aqueous persulfate salt-containing composition | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-12 | — | — | EP | claimed |
| EP-0913463-A1 | Multi-purpose liquid aqueous bleaching compositions | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-06 | — | — | EP | claimed |
| EP-0913462-A1 | Liquid aqueous bleaching compositions packaged in a UV-resistant container | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-06 | — | — | EP | claimed |
| EP-0913515-A1 | Process of bleaching fabrics | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-06 | — | — | EP | claimed |
| WO-1999023294-A1 | PROCESSES OF BLEACHING FABRICS | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-14 | — | — | WO | disclosed |
| WO-1999023197-A1 | PROCESSES OF SOAKING FABRICS WITH A LIQUID AQUEOUS PERSULFATE SALT-CONTAINING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-14 | — | — | WO | disclosed |
| WO-1999023196-A1 | LIQUID AQUEOUS BLEACHING COMPOSITIONS PACKAGED IN A UV RESISTANT CONTAINER | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-14 | — | — | WO | disclosed |
| WO-1999023195-A1 | MULTI-PURPOSE LIQUID AQUEOUS BLEACHING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-14 | — | — | WO | disclosed |
| EP-0915150-A1 | Processes of soaking fabrics with a liquid aqueous persulfate salt-containing composition | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-12 | — | — | EP | disclosed |
| EP-0913463-A1 | Multi-purpose liquid aqueous bleaching compositions | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0913462-A1 | Liquid aqueous bleaching compositions packaged in a UV-resistant container | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0913515-A1 | Process of bleaching fabrics | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |