Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28135738 | 0.85 | ALDH1A1 (0.49) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL6128323 | 0.84 | ALDH1A1 (0.54) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL6674072 | 0.83 | ALDH1A1 (0.53) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL8809974 | 0.80 | RAB9A (0.49) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL27713290 | 0.78 | ALDH1A1 (0.49) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL8062062 | 0.78 | ALDH1A1 (0.55) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL27713289 | 0.77 | ALDH1A1 (0.50) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL22717094 | 0.77 | CES1 (0.44) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL22535897 | 0.76 | ALDH1A1 (0.53) | ALDH1A1LMNATDP1MAPK1L3MBTL1 | |
| SCHEMBL6945759 | 0.76 | ALDH1A1 (0.53) | CA1CA2CA9CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021869-A1 | ERYTHROMYCIN A, 11,12-CARBAMATE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |