Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 17/20 | 0.64 |
| ▸ | RARB | P10826 | 10/20 | 0.64 |
| ▸ | RARA | P10276 | 9/20 | 0.64 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.53 |
| ▸ | RXRA | P19793 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5845874 | 0.91 | RARG (0.77) | RARGRARBRARARXRA | |
| SCHEMBL2580188 | 0.84 | RARG (0.80) | RARGRARBRARARXRA | |
| SCHEMBL2581862 | 0.83 | RARG (0.80) | RARGRARBRARARXRA | |
| SCHEMBL5847006 | 0.82 | RARG (0.74) | RARGRARBRARARXRA | |
| SCHEMBL5847715 | 0.82 | RARG (0.76) | RARGRARBRARARXRA | |
| SCHEMBL5845460 | 0.80 | RARG (0.57) | RARGRARBRARARXRA | |
| SCHEMBL10002005 | 0.80 | RARG (0.92) | RARGRARBRARARXRA | |
| SCHEMBL5846275 | 0.78 | RARG (0.60) | RARGRARBRARARXRA | |
| SCHEMBL344900 | 0.78 | RARG (1.00) | RARGRARBRARARXRA | |
| SCHEMBL5847037 | 0.78 | RARG (0.81) | RARGRARBRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-A1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | Galderma Research & Development (FR) | 1999-11-03 | — | — | EP | disclosed |
| WO-1999010308-A1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RESEARCH & DEVELOPMENT (FR) | 1999-03-04 | — | — | WO | disclosed |