Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.53 |
| ▸ | CDC7 | O00311 | 9/20 | 0.49 |
| ▸ | DBF4 | Q9UBU7 | 9/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8341363 | 0.86 | MAPT (0.78) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL10064831 | 0.85 | MAPT (0.62) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL8344773 | 0.85 | TRPM8 (0.70) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL24303679 | 0.85 | MAPT (0.62) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL5899899 | 0.84 | CDC7 (0.68) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL5641718 | 0.84 | CDC7 (0.68) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL17291419 | 0.83 | CDC7 (0.70) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL5937216 | 0.82 | PTPN11 (0.58) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL8338965 | 0.82 | SMN1; SMN2 (0.45) | KDM4ECDC7DBF4FNTAFNTB | |
| SCHEMBL5937223 | 0.81 | PTPN11 (0.53) | MAPTMEN1KMT2AKDM4EHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888941-A | Carbozamides with antifungal activity | J. URIACH & CIA. S.A. (ES) | 1999-03-30 | — | — | US | disclosed |
| EP-0783502-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-07-16 | — | — | EP | disclosed |
| WO-1997005131-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |