Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8341574 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL8338941 | 0.83 | ALDH1A1 (0.54) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL16703796 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL4497703 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL8345836 | 0.82 | MAPT (0.58) | KDM4EFNTAFNTBCDC7DBF4 | |
| SCHEMBL24303680 | 0.82 | RAB9A (0.48) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL873941 | 0.82 | RAB9A (0.48) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL28677825 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL5899840 | 0.79 | RAB9A (0.70) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL5937204 | 0.77 | RAB9A (0.44) | SMN1; SMN2KDM4ERAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888941-A | Carbozamides with antifungal activity | J. URIACH & CIA. S.A. (ES) | 1999-03-30 | — | — | US | disclosed |
| EP-0783502-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-07-16 | — | — | EP | disclosed |
| WO-1997005131-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |