Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 14/20 | 0.69 |
| ▸ | RARG | P13631 | 13/20 | 0.69 |
| ▸ | RARA | P10276 | 13/20 | 0.69 |
| ▸ | RXRA | P19793 | 5/20 | 0.58 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5845461 | 0.86 | RARB (0.92) | RARBRARGRARARXRARXRB | |
| SCHEMBL7794231 | 0.86 | RARB (0.64) | RARBRARGRARARXRARXRB | |
| SCHEMBL13283895 | 0.84 | RARG (0.71) | RARBRARGRARARXRATP53 | |
| SCHEMBL4965729 | 0.84 | RARB (0.69) | RARBRARGRARARXRARXRB | |
| SCHEMBL5846170 | 0.83 | RARB (0.60) | RARBRARGRARARXRA | |
| SCHEMBL7793710 | 0.83 | RARB (0.62) | RARBRARGRARARXRA | |
| SCHEMBL7794229 | 0.82 | RARB (0.75) | RARBRARGRARARXRARXRB | |
| SCHEMBL3677978 | 0.82 | RARB (1.00) | RARBRARGRARARXRARXRB | |
| SCHEMBL6730349 | 0.81 | RARB (0.61) | RARBRARGRARARXRA | |
| SCHEMBL8350702 | 0.81 | RARG (0.64) | RARBRARGRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-A1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | Galderma Research & Development (FR) | 1999-11-03 | — | — | EP | claimed |
| WO-1999010308-A1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RESEARCH & DEVELOPMENT (FR) | 1999-03-04 | — | — | WO | claimed |