Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13125057 | 0.87 | CTSK (0.69) | CTSKGPR4 | |
| SCHEMBL8346784 | 0.87 | GPR4 (0.48) | CTSKGPR4 | |
| SCHEMBL8344109 | 0.87 | GPR4 (0.52) | CTSKGPR4 | |
| SCHEMBL8345696 | 0.82 | CTSK (0.45) | CTSKGPR4 | |
| SCHEMBL8344404 | 0.81 | GPR4 (0.69) | CTSKGPR4 | |
| SCHEMBL8344244 | 0.79 | CTSK (0.52) | CTSKGPR4 | |
| SCHEMBL8344278 | 0.78 | CTSK (0.67) | CTSKGPR4 | |
| SCHEMBL3450386 | 0.77 | CTSK (0.67) | CTSKGPR4 | |
| SCHEMBL3450758 | 0.77 | CTSK (0.67) | CTSKGPR4 | |
| SCHEMBL3450761 | 0.77 | CTSK (0.67) | CTSKGPR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537111-B1 | HETEREOARYL NITRILE DERIVATIVES | NOVARTIS AG (CH) | 2007-05-02 | — | — | EP | disclosed |
| WO-2004020441-A1 | HETEREOARYL NITRILE DERIVATIVES | NOVARTIS AG (CH) | 2004-03-11 | — | — | WO | disclosed |