Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25634142 | 0.85 | DDB1 (0.54) | GPR119MAPTALDH1A1LMNADDB1 | |
| SCHEMBL25631758 | 0.85 | DDB1 (0.53) | GPR119MAPTALDH1A1LMNADDB1 | |
| SCHEMBL8352974 | 0.84 | GPR119 (0.59) | GPR119MAPTALDH1A1LMNAUSP30 | |
| SCHEMBL27091618 | 0.82 | NAMPT (0.52) | GPR119MAPTDDB1CRBNMEN1 | |
| SCHEMBL25631762 | 0.82 | DDB1 (0.51) | GPR119MAPTALDH1A1LMNADDB1 | |
| SCHEMBL21876731 | 0.82 | GPR119 (0.59) | GPR119MAPTALDH1A1LMNADDB1 | |
| SCHEMBL2959519 | 0.82 | GPR119 (0.74) | GPR119MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7435316 | 0.81 | GPR119 (0.57) | GPR119MAPTALDH1A1LMNAOPRM1 | |
| SCHEMBL8354642 | 0.81 | GPR119 (0.62) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL13313520 | 0.80 | GPR119 (0.59) | GPR119MAPTALDH1A1LMNADDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999020606-A2 | PIPERIDINES AND PIPERAZINES AS PLATELET AGGREGATION INHIBITORS | J. URIACH & CIA. S.A. (ES) | 1999-04-29 | — | — | WO | disclosed |