Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.40 |
| ▸ | RXRG | P48443 | 14/20 | 0.40 |
| ▸ | RXRB | P28702 | 13/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351713 | 0.92 | RXRA (0.38) | RXRARXRGRXRBPTPN1CYP26A1 | |
| SCHEMBL8347055 | 0.88 | RXRA (0.43) | RXRARXRGRXRBPTPN1CYP26A1 | |
| SCHEMBL8346572 | 0.86 | RXRA (0.40) | RXRARXRGRXRBPTPN1CYP26A1 | |
| SCHEMBL8556722 | 0.83 | RXRA (0.43) | RXRARXRGRXRBPTPN1RARB | |
| SCHEMBL8347375 | 0.83 | RXRA (0.40) | RXRARXRGRXRBPTPN1CYP26A1 | |
| SCHEMBL8555716 | 0.83 | RXRA (0.44) | RXRARXRGRXRBPTPN1HNF4A | |
| SCHEMBL8353225 | 0.82 | RXRA (0.39) | RXRARXRGRXRBPTPN1CYP26A1 | |
| SCHEMBL8350408 | 0.82 | RXRA (0.39) | RXRARXRGRXRBPTPN1CYP26A1 | |
| SCHEMBL8349950 | 0.82 | RXRA (0.39) | RXRARXRGRXRBPTPN1CYP26A1 | |
| SCHEMBL8352422 | 0.82 | RXRA (0.39) | RXRARXRGRXRBPTPN1CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935585-A | Biaromatic amido compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-08-10 | — | — | US | claimed |
| US-5935585-A | Biaromatic amido compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-08-10 | — | — | US | disclosed |