Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348009 | 0.87 | CTSS (0.60) | CTSSCTSKMAPTSMN1; SMN2HPGD | |
| SCHEMBL8337352 | 0.87 | CTSS (0.60) | CTSSCTSKMAPTSMN1; SMN2HPGD | |
| SCHEMBL6716729 | 0.83 | PGR (0.45) | PGRSCN1ASCN2ASCN3AMAPT | |
| SCHEMBL8327841 | 0.81 | CTSS (0.41) | CTSSCTSKMAPTALDH1A1TP53 | |
| SCHEMBL8347748 | 0.80 | PGR (0.53) | PGRSCN1ASCN2ASCN3AMAPT | |
| SCHEMBL8336805 | 0.79 | CTSS (0.57) | CTSSCTSKMAPTNPC1RAB9A | |
| SCHEMBL3648561 | 0.78 | CTSS (0.49) | CTSSCTSK | |
| SCHEMBL1095127 | 0.78 | CTSS (0.49) | CTSSCTSK | |
| SCHEMBL1105000 | 0.78 | CTSS (0.49) | CTSSCTSK | |
| SCHEMBL8345568 | 0.77 | NPC1 (0.45) | CTSSCTSKPGRSCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |